The wild idea of independence through the regional body
from other regional initiatives, all by somehow committing the same original sin.
To summarize the matter, all the listed attempts, as well as the Catalan one, they have shown that they are unpackable, And they are certainly destined to lead to anything, not even on the political level and/or individual prebends.
Evidently for the proponents it is not obvious that a state never allows a region to make a secession, But these mechanisms exist and are very strong. You should basically question the idea, absurd, that the state does not react. Each good project should indeed foresee these reactions, and trace some solutions. Otherwise you put a monkey behind the wheel of the plane, or worse, someone who wants to educate the oppressed peoples not to try to escape.
Instead all the constitutions of the world contain mechanisms that prevent these events, Obviously to guarantee the unit of the system.
The only exception are the constitutions of the confederations of states, that